![]() The Wavvy effect adds curvaceous distortion which I mapped to a macro along with a Reverb and Chorus combination on the audio chain of the Instrument Rack. I then added a HueSaturation effect to make it black and white by reducing the Saturation completely, then used a BrightnessContrast to make the image more stark. Once again, I grouped this into an Instrument Rack along with a percussive audio sample so the video chops would correspond to an audible component. I found some footage of snow falling outside my flat this past winter, which I dropped into Videosync’s Simpler in Slice mode. Their Simpler also comes with a handy Opacity to Velocity dial so the intensity of incoming notes governs the visibility of video output. Fade In, Fade Out, screen fill options and familiar Warp settings round out the primary features. Just drag and drop any supported video file (MOV and MP4 both worked fine), select your playback mode, and a range of the video’s length to loop. ![]() Videosync’s brilliant video Simpler works more or less like the audio version. ![]() To get more intricate, I could put different instances of Squares with different effects and settings on each individual Drum Rack pad, but the current set-up seems to be working well enough. With only one Column in Squares, I then added a ColorControl to make the resulting horizontal lines orange, followed by a Mirror effect to flip the lines vertically, placing the lines corresponding to kick drums at the bottom rather than the top. Grouping them also allows me to map Live devices and Videosync parameters to the same macros for enhanced audio-visual coherence. This means they both receive the same MIDI notes and react accordingly. In my case, I grouped an instance of Squares to an Instrument Rack along with a Drum Rack. In and of itself, it seems there’s not much to Squares, but it’s best approached as an elemental starting point: just add a few of Videosync’s effects and these basic shapes come to life rather quickly. Opacity adjusts the visibility of the boxes on entry and exit, while Size allows for growing and shrinking on each trigger. Conversely, set Rows to 1 with multiple Columns and you’ll get vertical lines instead. Columns and Rows determine the number of rectangles triggered by MIDI reduce Columns to 1 and you’ll see only horizontal lines, since there’s no horizontal division. ![]() The first step is to configure the Start Note to correspond with the MIDI fed into it the default is C3, but for most Drum Rack configurations it should be set to C1. The first is Squares, a seemingly utilitarian device that simply produces an array of white boxes. Videosync comes with two instruments that use MIDI signals to trigger visual output. Combined with Push2 it’s a powerful proposition in a live context. In essence, you really can use Ableton Live to make a music video. Combining just a few instruments and effects easily generates compelling visuals in real-time. In this tutorial, we show you how to make a music video in Ableton Live 11 using Videosync.ĭesigned for touring performers, multimedia artists, and forward-thinking laptop musicians, Videosync offers a suite of powerful yet intuitive Max for Live devices that seamlessly integrate video playback, audio reactivity, and flexible effects in Live 10 and 11. ![]()
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![]() Use the right-hand column to browse categories (nature, people, food, etc) or search by dominant color, which is ideal when you’re looking for cohesiveness in your design!īe sure to filter down to CC0 licensed images, since some photos do require attribution. Magdeline is another high-quality resource for free stock photography that doesn’t look like stock. You’ll also want to be sure that a release was obtained by the author or yourself for images of people or property. Public Domain Pictures includes lots of high-quality free public domain images, although some photos are only available with a premium membership to the site.īe sure to check the license listed on each individual photo, since some require that your credit the author (not great for commercial designs). FlickrCommons’ images contain no known copyright restrictions, but (as always) it’s not a guarantee-so do your research. It’s a great resource for finding free public domain images from all over the world, not just from the United States. Worldwide, archives and libraries partner with FlickrCommons and contribute their own public domain images. All photos on the site can be copied, modified and distributed (including for commercial purposes) under a custom license (that is essentially the same as a CC0 license), without you having to ask permission or provide attribution. They are now a creative community with millions of engaged users and 250,000+ exclusive photos. ![]() Unsplash is made up of a collective of photographers who were sick of “traditional” stock imagery, so they decided to offer their own high-resolution images for free. Please note that Wikimedia Commons does not guarantee the correctness of the licensing for each image, so make sure to triple-check the license tag for each individual image 2. Unsplash You can read more information about that here. Most of images can be used freely, but some of the images have certain restrictions. Wikimedia Commons is one of the largest public domain images resources. Museums, libraries and photographers sick of “traditional” stock photos have released thousands of public domain images online, making them more easily available to the public and (yep!) that means designers, too. In this article, we’ve compiled a list of websites curating free public domain images and high quality stock photography that can be freely used by anyone worldwide. The copyright for the image has expired.The image is assigned to the public domain through a Creative Commons Zero (CC0) license or similar release.These images can be used by almost anyone for personal and commercial purposes. There are three ways that public domain images occur: A public domain image is defined as a photo, clip art or vector whose copyright has expired or never existed in the first place. ![]() ![]() Over the last decade, the value of inducing ferroptosis, as well as its linkage with cancer therapy, has been noticed. GPX4 catalyzes the conversion of lipid peroxide at the expense of glutathione to prevent cells from undergoing ferroptosis.Ĭancer cells are usually under constant oxidative stress, yet ferroptosis seldom occurs due to the delicate equilibrium between catalytic irons and thiols. RS元 acts as a ferroptosis inducer by inactivating glutathione peroxidase 4 (GPX4), an anti-oxidant enzyme that protects cells against membrane lipid peroxidation. In this process, iron serves as a catalytic agent to convert peroxides into free radicals. It occurs when cells encounter ambient oxidative stress, with the massive membrane lipid peroxidation compromising the selective permeability of the plasma membrane. Ferroptosis is an iron-dependent and lipid-peroxidation-driven form of cell death. Previous studies have revealed that EVO exerts its cytotoxic effect by increasing the amount of reactive oxygen species (ROS) in cancer cells, and ROS can be amplified in a positive feedback loop. However, the precise mechanism of this multifaceted anti-cancer activity of EVO remains obscure. EVO causes G2/M cell cycle arrest and suppresses tumor cell invasion and metastasis. It is suggested that EVO acts in synergy with a target therapy or chemotherapeutic agents when multidrug resistance occurs in tumor cells. However, the literature discussing the anti-cancer effect of EVO in bladder UC is currently limited. It has been demonstrated to exhibit anti-cancer activities in non-small-cell lung cancer, hepatocellular carcinoma (HCC), leukemia, and breast cancer. Evodiamine (EVO), one of the quinazoline alkaloids, is an essential isolated from the seeds of Evodia rutaecarpa (Wu-Zhu-Yu). Some natural compounds extracted from herbs have been considered as potential adjuvants to enhance the anti-neoplastic ability of current medication. In conclusion, EVO is a novel inducer for activating the ferroptosis of bladder cancer cells and may be a potential therapeutic agent for bladder cancer. ![]() The TCCSUP bladder tumor xenograft tumor model confirmed the effects of EVO on the inhibition of tumor growth and EMT. Furthermore, EVO suppressed the migratory ability, decreased the expression of mesenchymal markers, and increased epithelial marker expression, determined by a transwell migration assay and Western blotting. These results indicate that EVO induces ferroptosis rather than apoptosis or necroptosis. Co-treatment with a pan-caspase inhibitor or necroptosis inhibitor with EVO did not alleviate cancer cell death. DFO also attenuated EVO-induced cell death. The lipid peroxide level significantly decreased when cells were treated with DFO prior to EVO treatment. ![]() ![]() Given the features of iron dependency and lipid-peroxidation-driven death in ferroptosis, the iron chelator deferoxamine (DFO) was used to suppress EVO-induced ferroptosis. GPX4, which catalyzes the conversion of lipid peroxides to prevent cells from undergoing ferroptosis, was decreased dose-dependently by EVO treatment. Lipid peroxides were detected by fluorescence microscopy after cancer cell exposure to EVO. Our results showed that EVO inhibited the cell proliferation of poorly differentiated, high-grade bladder cancer TCCSUP cells in a dose- and time-dependent manner. To determine whether ferroptosis is involved in the therapeutic effects of EVO, we investigated critical factors, such as lipid peroxidation levels and glutathione peroxidase 4 (GPX4) expression, under EVO treatment. Evodiamine (EVO) exhibits anti-cancer activity through the inhibition of cell proliferation however, little is known about its underlying mechanism. ![]() ![]() ![]() How many FPS will I get on Hogwarts Legacy? Hogwarts Legacy FPS - what frame rate can you expect? We'll help you find the best deal for the right gear to run the game. Filter for Hogwarts Legacy graphics card comparison and CPU compare. Looking for an upgrade? Try our easy to use Hogwarts Legacy set up guides to find the best, cheapest cards. Hogwarts Legacy will run on PC system with Windows 10 and upwards.
![]() ![]() All of these abilities enhance one's capacity to successfully manage the problems of daily living while remaining as self-sufficient as possible. A daily dose of crossword puzzles, according to the Alzheimer's Association, is a vital strategy to keep the brain busy and sharp, especially as you become older. Dementia can stay at bay with a crossword puzzle a day. There are other crossword advantages that are not immediately connected to intellect. A crossword puzzle is a fantastic technique to bring your body and mind into a state of relaxation. The more mindfulness you can accomplish, the less worried you will get. ![]() They can also increase social connection, emotions of intimacy, and collaborative problem solving when done with others. Additionally, if you've ever been irritated trying to figure out a word, you know that completing these frequently complex puzzles may improve your emotional control and stress tolerance. Controlling your emotions and stress is essential in long-term physical and mental health. Crossword puzzles can also help you relax by enhancing your sense of competence and providing you with something else to think about outside your daily worries. ![]() The benefits of word search puzzles have far-reaching implications on a multitude of aspects of your life. When you do crossword puzzles on a regular basis, you will not only learn new vocabulary, but you will also learn new things in general, especially if you collaborate with others to answer challenging riddles. The majority of crossword puzzles include a range of knowledge. You may learn something new about history, entertainment, science, technology, politics, and a variety of other topics. ![]() When you crack something or solve a difficult crossword challenge, you are ecstatic. The sense of accomplishment is the same no matter how old they are. This is one of the critical benefits of crossword puzzles and why they appeal to men and women of all generations. If you've never done something like this before, you should absolutely give it a shot. It may appear not very easy at first, but it will become second nature once you get the hang of it. It would be best if you also started with beginner crossword puzzles. Just until you find out how things operate, you know. If you're having trouble solving the challenge, feel free to utilize any of our crossword puzzle solutions below. When solving a crossword puzzle, you will be given multiple clues that are difficult to comprehend, perplexing, and frequently deceptive. As a result, your brain is forced to think beyond the box to solve an intellectually stimulating crossword problem. Thinking on a hint in numerous ways stimulates your creativity, which you may use in other aspects of your life. They Help Improve Cognitive Abilitiesĭo crossword puzzles make you smarter? It’s a timeless question. Well, people enjoy crossword puzzles for a variety of reasons, one of which is that it makes them more intelligent. I’d never heard of the creature.It makes them think, which helps them to develop their cognitive capacities. In Saturday’s New York Times puzzle, I was down to four blocks when I “cheated” (no cheating that’s another life lesson) and looked up “axolotyl,” an amphibian that rhymes with "bottle" in an Ogden poem. For example, one clue in a recent puzzle was “even things.” Instead of a plural noun, the answer was the verb "atone." Meanwhile, another recent clue was "biblical mount" and the answer wasn’t a mountain (like Sinai or Moriah), but a ride (“ass,” as in donkey). Mulling through the various meanings of words is imperative in solving crossword puzzles. My late father, who was inherently funny, practically spun an entire stand-up comedy routine over the fact that he, or someone else, read, in a camera’s instructions, the noun "wind" (like Oklahoma’s blowing down the plain) versus the verb "wind" (like twist). A fond memory of my childhood was when I was a preteen celebrating Christmas with a slew of relatives at my maternal great-aunt’s home in Okay, Oklahoma. ![]() ![]() ![]() The best-known stories (The Hare and the Tortoise, The Lion and the Mouse, The Fox and the Crow) are included in the collection, perfect for KS1 children. It would be great if Fable 4 let you have a cat that would occupy one of your houses and maraud the streets at night. A mortal has been accidentally placed onto Olympus. The resource is free to use.Īlso recommended is The Orchard Book of Aesop's Fables (£12.99, Orchard Books), a new retelling from Michael Morpurgo, with illustrations by Emma Chichester Clark. A world of people born into magnificent powers where bloodshed controls life. The Three Little Pigs Little Red Riding Hood The Velveteen Rabbit Jack and the Beanstalk The Tale of Peter Rabbit The Elves and the Shoemaker The Bogey-Beast Winnie The Pooh My Fathers Dragon St. As students read the fable, they’ll answer comprehension questions associated with the story. The charity Save a Cow has produced a free collection of African fables to download, including Why the Warthog is on his knees (Zulu) and How the Desert came to be (Ghana).Īsk them plenty of questions about the characters to help them with reading comprehension, including questions where retrieval of information is required (‘Who else was running in the race?’) as well as questions that rely on inference (‘Can you find a sentence that tells us that the hare was over-confident?’) and also questions that rely on deduction (‘What do you think the tortoise was thinking as he was doing the race?’).Ī is an enormous and comprehensive online collection of 655+ fables, indexed in table format, with morals listed. This resource comes with 10 different color-by-numbers associated with traditional fables like The Tortoise and the Hare, The Crow and the Pitcher, and The Town and the Country Mouse. The majority of fables use animals that talk, and they are usually used as teaching tools. Free Aesop fables to listen to are available on the Storynory website. Fables have been told to children for centuries. 1) A truly open world: Fable games had decent-sized worlds for their time, but theres no denying even Fable. You can help your child at home by reading fables with them and encouraging them to talk about what they have read. Here are six things we want to see in the upcoming game. ![]() |